According to The New York Times, studies show us that early hunters, who depended on their feet to outrun their dinner, weren't as accident prone as we are today [...] Running on only artificial surfaces and in high-tech shoes can change the biomechanics of running, increasing the risks of injury. What's the solution? Slower, easier training over a long period would most likely help; so would brief walk breaks, which mimic the behavior of the persistence hunter. [...] Unlike most animals, our bodies are meant to run long distances. We're engineered from top to bottom to run as much as our hearts desire. Our downfall is where we choose to do our running and the intensity in which we run. Especially going into the fall months, many with a regimented workout routine will turn indoor to gyms or home equipment. Even though a few miles on a track or treadmill will keep your heart rate up, they aren't the best way to prevent injury (even with new fancy shoes). [...] Try running shorter distances outside and take frequent walking breaks to mix things up. Streets and sidewalks are okay, but running hills at your local park would be even better, and if the weather allows (it probably won't), try a few runs barefoot to take it things one step further.
source : Run like a hunter oraz New York Times - The Human Body Is Built for Distance